Cthrc1 kda

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August undefined, 2024

Web~Two bands of 25-30 kDa (SDS-PAGE) Purity: ≥90% (SDS-PAGE) Endotoxin Content: 0.01EU/μg purified protein (LAL test). Concentration: 0.1mg/ml after reconstitution. ... Collagen triple helix repeat containing-1 (CTHRC1) is a 30kDa glycosylated secretory protein containing a short collagen-like motif contributing to vascular remodeling by ... WebApr 15, 2002 · Hepatocellular carcinoma (HCC) Malignant behaviors microRNA-155-5p (miR-155-5p) Collagen triple helix repeat containing 1 (CTHRC1) GSK-3β-involved Wnt/β-catenin signaling; ... Osteosarcoma microRNA-338-3p Activator of 90 kDa heat shock protein ATPase homolog 1 Tumor suppressor Translational repression; 82.

CTHRC1 Antibody (NBP2-31797): Novus Biologicals

WebFeb 8, 2024 · Collagen triple helix repeat containing 1 (CTHRC1) is an extracellular matrix protein that regulates tumor invasion and modulates the tumor microenvironment. However, the association of CTHRC1 with the prognosis and tumor-infiltrating lymphocytes of KIRP and KIRC has not been reported. WebOct 6, 2024 · Collagen triple helix repeat containing 1 (CTHRC1), a 30 kDa protein is generally expressed in developing bones, cartilage, and myofibroblasts during wound healing 5. how to run a printer test

CTHRC1 - Antibodies - The Human Protein Atlas

WebThe recombinant human CTHRC1 consists of 224 amino acids and has a predicted molecular mass of 24.5 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh CTHRC1 is approximately … WebCollagen triple helix repeat containing protein 1 (CTHRC1) is a 30 kDa secreted glycoprotein encoded by the CTHRC1 gene. CTHRC1 is known to regulate extracellular collagen deposition and partake in vascular remodeling of arterial injury as a function of cellular response through the TGF-β and Wnt pathways. Moreover, WebProteolytic processing may generate multiple CTHRC1 isoforms. There is the potential for an intracellular full-length 33 kDa, 245 aa form, plus extracellular isoforms that are 28 kDa (aa 33-245), 26 kDa (aa 49-245), 20 kDa (aa 98‑245) and 18 kDa and 16 kDa in size, the last two representing variants of the 20 kDa form with C-terminal processing. how to run a printer power cycle

CTHRC1 promotes liver metastasis by reshaping …

CTHRC1 (human) (recombinant protein) - Order from Adipogen

WebMay 13, 2024 · CTHRC1 is highly expressed in patients with primary CRC and hepatic metastasis of CRC and predicts a poor prognosis. To identify the potential metastasis-associated genes in primary CRC, we first ... WebMay 22, 2024 · Collagen triple helix repeat containing 1 (CTHRC1), a secreted ECM protein, is a 28-kDa evolutionarily conserved extracellular matrix glycoprotein, containing an NH2-terminal signaling peptide for extracellular secretion, a short collagen triple helix repeat of 36 amino acids, and a COOH-terminal globular domain . how to run a private ark serverWebCTHRC1 is overexpressed in multiple human cancers, and its expression is associated with increased migration and metastasis, as well as decreased survival (1-3). CTHRC1 expression is regulated through TGF-β/Smad3 … northern outfitter boots

"WebAug 12, 2024 · CTHRC1 expresses mainly in adventitial fibroblasts and neointimal smooth muscle cells of balloon-injured vessels and promotes cell migration and tissue repair in response to injury. CTHRC1 plays a ... " - Cthrc1 kda

Cthrc1 kda

Recombinant Human Collagen triple helix repeat-containing protein 1(CTHRC1)

WebAll lanes : Anti-CTHRC1 antibody (ab264410) at 1/1000 dilution Lane 1 : UACC-62 whole cell lysate Lane 2 : MALME-3M whole cell lysate Lane 3 : SR whole cell lysate Lane 4 : HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate Lysates/proteins at 50 µg per lane. Developed using the ECL technique. Predicted band … WebCollagen triple helix repeat containing-1 (CTHRC1) is a 28-kDa secreted protein, reported to be involved in vascular remodeling, bone formation and morphogenesis [19]. In addition to functioning in the context of arterial injury, recent studies have reported CTHRC1 acts as a prognostic factor. Furthermore, it promotes tumor

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WebMar 1, 2005 · Collagen triple helix repeat containing 1 (CTHRC1) is a 28-kDa secreted glycoprotein containing a short collagen motif with 12 Gly-X-Y repeats, and it is highly conserved from lower chordates to ... WebThe molecular weight of secreted CTHRC1 (30 kDa) appears to be larger than that of cellular CTHRC1 (26 kDa). CTHRC1 has four different isoforms with molecular weights of about 12.3 kDa to 27 kDa ...

WebCTHRC1 protein expression summary. Single band larger than predicted size in kDa (+20%) but partly supported by experimental and/or bioinformatic data. WebAll lanes : Anti-CTHRC1 antibody (ab264411) at 1/1000 dilution Lane 1 : UACC-62 whole cell lysate Lane 2 : MALME-62 whole cell lysate Lane 3 : SR whole cell lysate Lane 4 : NIH/3T3 (mouse embryo fibroblast cell line) whole cell lysate Lysates/proteins at 50 µg per lane. Developed using the ECL technique. Predicted band size: 26 kDa Exposure time: …

WebOct 11, 2024 · Background Metastasis is the major cause of morbidity and mortality in patients with epithelial ovarian cancer (EOC), however the mechanisms that underline this process are poorly understood. Collagen triple helix repeat containing-1 (CTHRC1) is a 28-kDa secreted protein reported to be involved in vascular remodeling, bone formation … WebCollagen triple helix repeat containing 1: Protein class i. Disease related genes Human disease related genes: Predicted location i. Intracellular,Secreted ... 26.2 kDa Yes: 0: CTHRC1-202 ENSP00000416045 ENST00000415886: E7EVQ5 [Direct mapping] Collagen triple helix repeat-containing protein 1 . Show all.

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WebImmunohistochemistry-Paraffin: CTHRC1 Antibody [NBP2-31797] - Staining of human pancreas shows low positivity in glandular cells as expected. Immunohistochemistry-Paraffin: CTHRC1 Antibody [NBP2-31797] - Staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells. how to run a premortemWebCthrc1 is a 30 kDa secreted protein that has the ability to inhibit collagen matrix synthesis. Cthrc1 is also glycosylated and retains a signal sequence … We recently identified collagen triple helix repeat containing-1 (Cthrc1) as a novel gene induced in adventitial fibroblasts after arterial injury. northern outdoors katahdinWebAnti-CTHRC1 antibody [EPR22851-145] (ab256458) Research with confidence – consistent and reproducible results with every batch. Long-term and scalable supply – powered by recombinant technology for fast production. Success from the first experiment – confirmed specificity through extensive validation. Ethical standards compliant ... northern outfitters boots for saleWebCTHRC1 (Collagen triple helix repeat-containing protein 1) is a 28-30 kDa, secreted glycoprotein that bears similarity to the C1q/TNF alpha -related family of proteins. It is expressed by disparate cell types, including renal epithelium, neurons, osteoblasts, and smooth muscle cells. northern outfitters clothingWebOct 26, 2024 · The function of collagen triple helix repeat containing 1 (CTHRC1) as an oncogene has been reported in a growing number of publications. ... Highly conserved from lower chordates to mammals, the CTHRC1 protein was identified as a 30 kDa secreted protein and was first verified to be a differentially expressed gene in balloon-injured rat … northern outfall sewer constructionWebCTHRC1 gene deletion leads to fatty liver (steatosis) formation in mice while others exhibited inactivation of the CTHRC1 gene also results in low bone mass. Description. CTHRC1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 234 amino acids (31-243 a.a) and having a molecular mass of 25.3kDa. ... how to run a private practiceWebOct 11, 2024 · Collagen triple helix repeat containing-1 (CTHRC1) is a 28-kDa secreted protein reported to be involved in vascular remodeling, bone formation and morphogenesis. This study aimed to investigate the role of CTHRC1 in promoting the metastasis of EOC and to elucidate the underlying molecular mechanisms. northern outdoors forks me