WebCisplatin was given intravenously once a week at a dose of 40 mg per square meter of body-surface area, with the total dose not to exceed 70 mg per week. A maximum of six doses of cisplatin was... WebMethods: This retrospective analysis included women with locally advanced cervical cancer treated with NACT-CCRT between September 2011 and September 2014. Neoadjuvant …
Improvement in radiation techniques for locally advanced …
WebApr 19, 2024 · Cisplatin and carboplatin are two platinum drugs commonly used in chemotherapy. It is investigated that the main role of chemotherapy in CCRT is to enhance the sensitivity of radiotherapy (RT), and carboplatin concomitant with RT has similar efficacy and safety with single cisplatin [ 25, 26 ]. Similarly, another study confirmed this … WebMay 8, 2006 · Evidence from the GOG125 study indicates that weekly cisplatin at 40 mg/m 2 for six weeks is equally effective yet less toxic than cisplatin and 5-fluorouracil in a classic 21-day schedule [ 13 ]; nonetheless, the choice of 40 mg/m 2 as the dose for weekly cisplatin for phase III chemoradiation trials was not based on previous phase I data, and … gta san andreas main theme
Cisplatin versus gemcitabine as concurrent... : Journal of Cancer ...
WebJan 10, 2024 · Background Currently, the standard treatment for locally advanced cervical cancer is concurrent chemoradiation (CCRT). The effect of neoadjuvant chemotherapy in advanced cervical cancer is controversial. Studies have shown that the addition of a weekly regimen of neoadjuvant chemotherapy (NACT) followed by CCRT may be … WebAs a second-generation platinum derivative, nedaplatin has been demonstrated to be equivalent to or have superior antineoplasic activity to cisplatin with less toxicity in cervical cancer. 24–26 The majority of our patient population was administered with weekly nedaplatin. Grade 3 acute toxicities were observed in only 4 patients (14.3% ... WebPlatinum-based combination chemotherapy vs. weekly cisplatin during adjuvant CCRT in early cervical cancer with pelvic LN metastasis We found that platinum-based combination chemotherapy during adjuvant CCRT after surgery promoted better survival than a weekly cisplatin regimen in ECC patients with pelvic LN metastasis. gta san andreas main characters